Ashwagandha (Withania somnifera) also Indian ginseng or winter cherry. It has been known for thousands of years since it appeared as a beneficial herb in natural Indian medicine. Currently it is credited with anti-cancer, antibacterial, cytostatic, sedative and blood pressure-lowering properties.
It occurs naturally in tropical and sub-tropical climates and can therefore be found in South Africa, Sri Lanka, China, India and the Canary Islands. It grows in the form of shrubs up to 150 cm high. It can be recognized by its elongated, slightly mat leaves and orange-red fruits.
Ashwagandha owes its name to its specific, unpleasant smell – in Sanskrit, the combination of the words “ashwa” and “gandha” means: “horse smell”.
Indian ginseng owes its popularity to its active ingredients, which show a beneficial and holistic effect on the functioning of the body.
Witanolides are the most important compounds showing biological activity in the root and leaves of ashwagandha. Over 140 vitanolides from this plant have been thoroughly studied. They exhibit anticancer, antibacterial, cytostatic, sedative, and blood pressure-lowering properties. The best-studied is Withaferin A, whose proven anticancer activity is inhibition of factor Sp1. Sp1 factor helps maintain telomerase activity in cancer cells, contributing to their increased kongevity.
Withaferin A is responsible for the neuroprotective properties of Ashwaganda.
Another group of active substances present in the composition of Withania somnifera are alkaloids there are as many as 12 types of them. Alkaloids are characterized by antioxidant, anti-inflammatory and anti-anxiety effects.
Other active compounds contained in Indian ginseng include: sitoinosides (present in the root of the plant, show anti-stress and antioxidant activity) and flavonoids (showing activity limiting the growth of pathogenic microorganisms).
For an herb to qualify as an adaptogen, it must meet several conditions:
Ashwagandha meets all of these – it is the most studied adaptogen, which is why it is often called: “queen of adaptogens” – numerous studies have shown that its regular use stabilizes physiological processes, strengthens resistance to stress and helps to better adapt to constantly changing external factors.
Add titleAshwagandha – why use adaptogens?
Ashwagandha (Withania somnifera) also Indian ginseng or winter cherry. It has been known for thousands of years since it appeared as a beneficial herb in natural Indian medicine. Currently it is credited with anti-cancer, antibacterial, cytostatic, sedative and blood pressure-lowering properties.
It occurs naturally in tropical and sub-tropical climates and can therefore be found in South Africa, Sri Lanka, China, India and the Canary Islands. It grows in the form of shrubs up to 150 cm high. It can be recognized by its elongated, slightly mat leaves and orange-red fruits.
Ashwagandha owes its name to its specific, unpleasant smell – in Sanskrit, the combination of the words “ashwa” and “gandha” means: “horse smell”.
Indian ginseng owes its popularity to its active ingredients, which show a beneficial and holistic effect on the functioning of the body.
Witanolides are the most important compounds showing biological activity in the root and leaves of ashwagandha. Over 140 vitanolides from this plant have been thoroughly studied. They exhibit anticancer, antibacterial, cytostatic, sedative, and blood pressure-lowering properties. The best-studied is Withaferin A, whose proven anticancer activity is inhibition of factor Sp1. Sp1 factor helps maintain telomerase activity in cancer cells, contributing to their increased kongevity.
Withaferin A is responsible for the neuroprotective properties of Ashwaganda.
Another group of active substances present in the composition of Withania somnifera are alkaloids there are as many as 12 types of them. Alkaloids are characterized by antioxidant, anti-inflammatory and anti-anxiety effects.
Other active compounds contained in Indian ginseng include: sitoinosides (present in the root of the plant, show anti-stress and antioxidant activity) and flavonoids (showing activity limiting the growth of pathogenic microorganisms).
For an herb to qualify as an adaptogen, it must meet several conditions:
Ashwagandha meets all of these – it is the most studied adaptogen, which is why it is often called: “queen of adaptogens” – numerous studies have shown that its regular use stabilizes physiological processes, strengthens resistance to stress and helps to better adapt to constantly changing external factors.
In traditional ayurvedic formulas, natural methods are used as a form of raw material preparation – drying and grinding the root to the finest possible form. For dietary supplements, extracts of varying concentrations are used, which are based on aqueous or organic solvents.
Research on ashwagandha supplements confirms that it is safe to use in adequate amounts by healthy individuals. However, some people (especially those taking some specific drugs) should consult their doctor before starting Indian ginseng supplementation. What should you pay special attention to?
Thyroid disorders – the compounds in “ashwa” affect endocrine function. People with thyroid disorders should consult their doctor about the therapy.
Use of medications with central action – sleep aids, antidepressants, antiepileptic drugs. People taking medications from these groups should consult supplementation with a doctor.
Taking medications for hypertension and diabetes – ashwagandha may interfere with the effect of these groups of medications due to its hypotensive and hypoglycemic effects. It is a good idea to monitor blood pressure and sugar status while taking ashwagandha supplementation.
With which drugs can an ashwagandha supplement interact with?
Ashwgandha is a very versatile adaptogen – because of its broad spectrum of actions, it can be used for different purposes and for different ailments. Additionally, it is inclusive – thanks to its ever-growing popularity, we can find more and more inexpensive but good quality supplements on the market. Almost anyone can use ashwagandha, because there are few contraindications for its usage.
There are plenty of preparations and supplements containing ashwagandha extract available on the market today. It is worth knowing that in the case of plant raw materials, the most important issue we should look at is standardization. In the context of ashwagandha, it concerns, first of all, the previously mentioned vitanolides.
If the package of the supplement does not contain information on the amount of active compounds – it may turn out to be of questionable quality!
There is also the issue of choosing the form of the supplement. Ashwagandha can usually be found in three forms: in tablets, in capsules and in drops. There is also powdered ashwagandha root or leaf, from which a decoction should be prepared before consumption.
The dosage of ashwagandha, like any other supplement, depends on several factors. The most important of these are age, purpose of use, and overall health. Generalizing, the supplement is usually recommended to be taken in two doses per day – morning and evening.
Manufacturers recommend taking breaks during treatment with Indian ginseng. The effects of supplementation may be noticeable even after 2-3 months, however, it is recommended to take a one-month break in using the extract every 8 weeks due to rapid adaptation of the body to active substances. The supplement, in any form, should be consumed after a meal.
All manufacturers clearly recommend that ashwagandha extract supplements should not be used during pregnancy and lactation. Higher miscarriage rates have been reported with high doses of the extract!
In conclusion, supplementation with ashwagandha extract is a very versatile choice, as it will work on number of our body systems. There are many supplements available on the market, but it is worth paying attention to standardization when choosing. There are some contraindications to using the supplement, but it is perfectly safe for healthy individuals.VisibilityPublish
In traditional ayurvedic formulas, natural methods are used as a form of raw material preparation – drying and grinding the root to the finest possible form. For dietary supplements, extracts of varying concentrations are used, which are based on aqueous or organic solvents.
Research on ashwagandha supplements confirms that it is safe to use in adequate amounts by healthy individuals. However, some people (especially those taking some specific drugs) should consult their doctor before starting Indian ginseng supplementation. What should you pay special attention to?
Thyroid disorders – the compounds in “ashwa” affect endocrine function. People with thyroid disorders should consult their doctor about the therapy.
Use of medications with central action – sleep aids, antidepressants, antiepileptic drugs. People taking medications from these groups should consult supplementation with a doctor.
Taking medications for hypertension and diabetes – ashwagandha may interfere with the effect of these groups of medications due to its hypotensive and hypoglycemic effects. It is a good idea to monitor blood pressure and sugar status while taking ashwagandha supplementation.
With which drugs can an ashwagandha supplement interact with?
Ashwgandha is a very versatile adaptogen – because of its broad spectrum of actions, it can be used for different purposes and for different ailments. Additionally, it is inclusive – thanks to its ever-growing popularity, we can find more and more inexpensive but good quality supplements on the market. Almost anyone can use ashwagandha, because there are few contraindications for its usage.
There are plenty of preparations and supplements containing ashwagandha extract available on the market today. It is worth knowing that in the case of plant raw materials, the most important issue we should look at is standardization. In the context of ashwagandha, it concerns, first of all, the previously mentioned vitanolides.
If the package of the supplement does not contain information on the amount of active compounds – it may turn out to be of questionable quality!
There is also the issue of choosing the form of the supplement. Ashwagandha can usually be found in three forms: in tablets, in capsules and in drops. There is also powdered ashwagandha root or leaf, from which a decoction should be prepared before consumption.
The dosage of ashwagandha, like any other supplement, depends on several factors. The most important of these are age, purpose of use, and overall health. Generalizing, the supplement is usually recommended to be taken in two doses per day – morning and evening.
Manufacturers recommend taking breaks during treatment with Indian ginseng. The effects of supplementation may be noticeable even after 2-3 months, however, it is recommended to take a one-month break in using the extract every 8 weeks due to rapid adaptation of the body to active substances. The supplement, in any form, should be consumed after a meal.
All manufacturers clearly recommend that ashwagandha extract supplements should not be used during pregnancy and lactation. Higher miscarriage rates have been reported with high doses of the extract!
In conclusion, supplementation with ashwagandha extract is a very versatile choice, as it will work on number of our body systems. There are many supplements available on the market, but it is worth paying attention to standardization when choosing. There are some contraindications to using the supplement, but it is perfectly safe for healthy individuals.